Revolution (selamectin) Spot-On Solution for puppies is a monthly topical medication used to prevent and treat a variety of common canine parasites. Controls fleas, prevents flea eggs from hatching, and is indicated for the prevention of heartworm disease. Treats and controls ear mite infestations and certain intestinal worms like roundworms and hookworms. Kills adult fleas and prevents flea eggs from hatching, thus preventing flea infestations. For puppies as young as six weeks old. Prescription required.